. wrote:So, Kojiro, your thought process is first to degrade and or eliminate the scar tissue then when the skin heals your hope is that the cells will not duplicate the scar tissue? Do you believe slowly wearing down the skin with Retin-A and peels would work? I'm willing to give almost anything a try and this routine sounds logical but I imagine not one single routine will work for everyone. I know you have knowledge in the science of all this, do you think we can find something that really will work?
shoo
When are cut, a huge determinate of whether the skin heals with or without a scar is based on the size of the wound created. This has effects on TGF-beta levels, and a bunch of other factors which we are trying to understand. If the wound is small it can normally be healed without a scar even if it penetrates into the dermis. When stretch marks are formed it is after the entire dermis is split so of course we get scar tissue. The idea is we want to remove a little bit of the scar tissue each time we do a peel, just enough so that we are getting progress but not resulting in more scar tissue being put down. Of course we run into other problems like the fact that scar tissue is resiliant and meant to last a lifetime. It is also very hard to get things into the dermis. When we create small wounds the healing process follows, we usually don't have to do a whole lot to stimulate that. In my opinion it is breaking down the scar tissue slowly which is the hard part of the equation.













