Chelsea Handler "shut down" following her brother's death.
The 'Chelsea Lately' star was just 10-years-old when her big brother Chet died in a hiking accident aged just 22.
She said: "He was hiking in the Grand Tetons and he literally fell like 80 feet off a cliff."
The grief caused her to retreat into her own private world where she focussed her energy on not crying in front of people - a tactic she admits was not "healthy".
Appearing on 'The Rosie Show', the 36-year-old comedienne said: "I was shut down. I was shut down because I didn't want to cry in front of anyone. I had seen my parents cry, I was embarrassed.
"That's very unhealthy and took a long time to get over."
She also felt unnoticed by the rest of her family in the time following the tragedy, although it ultimately brought them closer.
She said: "I was used to walking into a room and having everyone pay attention to me and I couldn't get any attention. I was in pain too and I felt like no one was tending my pain.
"I also look back at that as one of the most informing things in my life."