Heather Locklear has called for prayers for Charlie Sheen after his HIV positive diagnosis was revealed.

Heather Locklear

Heather Locklear

The 54-year-old actress made a public declaration of support for her former 'Spin City' co-star by sharing a picture of them together on Instagram and writing: "My heart hurts. Prayers for Charlie and his family."

The National Enquirer first revealed Charlie's diagnosis before the 'Two and a Half Men' star confirmed it in an interview with Matt Lauer on the 'TODAY' show on Tuesday (17.11.15).

Charlie revealed that his ex-wives Denise Richards and Brooke Mueller have both been aware of his illness - which was diagnosed four years ago - for some time but he only recently told his oldest daughter Cassandra, 30.

Charlie, who also has daughters Sam, 11, and Lola, nine with Denise and twin boys Bob and Max, six with Brooke, said: "It hit her hard but she recovered, but she's tough like her dad...She was a rock star about it."

He also explained that he has paid out millions to blackmailers who threatened to reveal his illness but he is relieved that he is now free from extortion.

Charlie said: "We're talking about shakedowns. I've paid those people, not that many, but enough to bring it into the millions. That's money they're taking from my children. It's not just me. I've got five kids and a granddaughter. I release myself from this prison today.

"It'll be great again. I'm a survivor. I've been up I've been down I've been rich I've been poor. It's another chapter in my life. It's not commerce driven. It's socially driven."