Lexie, played by Chyler Leigh, died of her injuries in the season eight finale in last month, which closed with Meredith (Ellen Pompeo), Derek (Patrick Dempsey), Cristina (Sandra Oh), Mark (Eric Dance) and Arizona (Jessica Capshaw) still stranded in the wilderness.
Asked about the fate of the stranded Grey's chracters, Rhimes told TV Guide: "Just because you saw people alive at the end of the finale doesn't mean they're going to be alive when the season starts up."
Rhimes has confessed on Twitter that the writing of the finale which also featured the departure of Teddy (Kim Raver), was "incredibly hard to write."
"I did not enjoy it," Rhimes worte. "It made me sick and it made me sad."
"Lexie's death was a decision that Chyler and I came to together. We had a lot of thoughtful discussion about it and ultimately we both decided this was the right time for her character's journey to end."
Grey's Anatomy cast member Jesse Williams also acknowledged that it "was kind of depressing" to say goodbye to Leigh and Raver.
Tagged in Greys Anatomy