Charlie Sheen insists he hasn't infected anyone with HIV.

Charlie Sheen

Charlie Sheen

The former 'Two and a Half Men' star was diagnosed with the disease four years ago and despite previously claiming he has slept with more than 700 women, the 50-year-old actor is adamant he hasn't contaminated anyone.

Speaking on 'Good Morning Britain', he said: "But it's what people need to focus on and need to understand as absolute truth is that I have infected no-one.

"There is no-one coming at me saying, 'Well now ... you know', this has not happened."

Charlie - who has daughters Cassandra, 31, Sam, 12, and Lola, 11, and seven-year-old twin sons, Bob and Max - has claimed he once slept with a British home secretary's daughter, and insisted international police organisation Interpol would get involved if he said too much.

Speaking at an Evening with Charlie Sheen at the Theatre Royal to Piers Morgan, he said: "There was a girl here about 20 years ago. I can't say she was famous, but her father really was.

"And let's just say it was a race to the airport between parliament, my security team and Interpol.

"That's all I can say about to it because it's not fair."

When asked whether her father was British, Charlie - who revealed he has HIV last November - added: "Extremely.

"I didn't find out until - 'Wait a minute, your dad is who?' "

While Charlie initially refused to reveal any further details, saying "Interpol will be involved", he did finally admit her father was a former British home secretary.

The star recently claimed he only had unprotected sex twice.

He said: "[It happened] a couple of times. Twice. And we would be having a different dialogue."

When asked if that meant he had only had unprotected sex twice, he added: "Oh yeah. I was always the guy that promoted it and said you've got to use condoms, this and that. I was too drunk or too bored one night and here we are."