Debra Messing was left with a pepperoni-shaped cupping mark after undergoing the ancient suction treatment.

Debra Messing's pepperoni mark (c) Instagram

Debra Messing's pepperoni mark (c) Instagram

The 'Will and Grace' star took to Instagram on Wednesday evening (05.04.17) to share a photo of the aftermath of the skin suction treatment which is supposed to improve blood flow and ease pain and inflammation.

Debra, 48, was freaked out by the "crazy" mark and was panicking as she had a day of interviews on Thursday (06.04.17).

Alongside the picture of the round-shaped red patch, she wrote: "How CRAZY is this cupping mark???? I have press tomorrow! Hope my dress covers all of it. (sic)"

Several celebrities are advocates of cupping including Gwyneth Paltrow, Nicole Richie and Jennifer Aniston.

Debra, like most women, is concerned with her appearance, and she recently shared that she was once told her nose was "ruining" a movie.

The flame-haired beauty was left devastated when filmmaker Alfonso Arau - who helmed her first film, 1995's 'A Walk in the Clouds' - told her to visit a plastic surgeon because he didn't like her hooter, and the incident left her confidence in tatters.

She recalled: "I'd never been on a film before. I was doing a love scene with Keanu Reeves. We started filming and the very famous director screamed 'Cut' and said, 'How quickly can we get a plastic surgeon in here? Her nose is ruining my movie.'

"It was a shock. I was so confident coming out of graduate school with my Masters in acting. I'd studied in London and I was so well equipped with skill sets, and then to walk on set and have that happen - I was reduced to an un-Hollywood nose."

It has taken Debra "years and years and years" to embrace her unique look and feels frustrated that Hollywood has such a "very narrow" definition of what is beautiful.

She said: "It's taken me years and years and years to finally own my differences and to love what's different about me, and to come face to face with a truth within my industry, within our culture.

"There is a very narrow definition of what a beautiful, vital, vibrant, interesting woman looks like, and that's the thing we're constantly fighting against. My entire career I've been swimming in that pond, where it's like, 'Oh no, you don't look right.' "

Debra is to reunite with Eric McCormack for a new 10-episode series of 'Will & Grace' for NBC.