Bradley Cooper, Zach Galifianakis, Ed Helms & Todd Philips
The Hangover Part III will be the last instalment of the comedy series.
Todd Philips is set to return to the director's chair for the final time as a much anticipated third Hangover movie will go ahead.
In a statement Philips said: "I'm so excited to embark on another Hangover film with Bradley, Ed and Zach.
"We're going to surprise a lot of people with the final chapter we have planned.
"It will be a fitting conclusion to our three-part opera of mayhem, despair and bad decisions."
The franchise has catapulted Bradley Cooper, Ed Helms, Justin Bartha and Zach Galifianakis to fame
The franchise has so far grossed in excess of $1 billion at the global box office and The Hangover Part II is the highest-grossing R-rated comedy of all time.
However Philips would give any details of the movie away and it is not yet known where the film will be set.